Chédin, Frédéric



Frederic Chedin.jpg (90724 bytes) Frédéric Chédin

DEA, Genetics, 1991 - University of Paris-Orsay (France)

Engineering Degree in Agronomy, 1991 - ENSA.M (France)

Ph.D., Genetics, 1995 - University of Paris-Orsay (France)

Visiting Postdoctoral Scholar, 1996-1999 - University of California, Davis, CA

  Current address:

Associate Professor
University of California
Molecular and Cellular Biology
332 Briggs Hall
1 Shields Ave
Davis, CA 95616
Tel: (530) 752-1800

Chédin, F., Dervyn, E., Dervyn, R., Ehrlich, S.D. and Noirot, P. (1994)
Frequency of deletion formation decreases exponentially with distance between short direct repeats.
Mol. Microbiol., 12, 561-569. PMID: 7934879.

Tracy, R.B., Chédin, F., and Kowalczykowski, S.C. (1997).
The recombination hot spot Chi is embedded within islands of preferred DNA pairing sequences in the E. coli genome.
Cell, 90, 205-206. PMID: 9244294. [Full Text] [PDF]

Chédin, F., Dervyn, R., Ehrlich, S.D. and Noirot, P. (1997)
Apparent and real recombination frequencies in multicopy plasmids: the need for a novel approach in frequency determination.
J. Bacteriol., 179, 754-761. PMID: 9006030; PMCID: PMC178757.

Chédin, F., Noirot, P., Biaudet, V. and Ehrlich, S.D. (1998)
A five-nucleotide sequence protects DNA from exonucleolytic degradation by AddAB, the RecBCD analogue of Bacillus subtilis
Mol. Microbiol., 29, 1369-1377. PMID: 9781875.

Pujol, C., Chédin, F., Ehrlich, S.D. and Janniere, L. (1998)
Inhibition of a naturally occurring rolling-circle replicon in derivatives of the theta-replicating plasmid pIP501.
Mol. Microbiol., 29, 709-718. PMID: 9723911.

Chédin, F., Seitz, E.M., and Kowalczykowski, S.C. (1998).
Novel homologs of replication protein A in Archaea: implications for the evolution of ssDNA-binding proteins.
Trends Biochem. Sci., 23, 273-277. PMID: 9757822. [Abstract] [Full Text] [PDF]

Chédin, F., Ehrlich, S.D., and Kowalczykowski, S.C. (2000).
The Bacillus subtilis AddAB helicase/nuclease is regulated by its cognate Chi sequence in vitro
J. Mol. Biol., 298
, 7-20. PMID: 10756102. [Abstract] [Full Text] [PDF]

Chédin, F. and Kowalczykowski, S.C.  (2002).
A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination.
Mol. Microbiol.  43, 823-834. PMID: 11929535.
[Full Text] [PDF]

Chédin, F., Handa, N., Dillingham, M.S., and Kowalczykowski, S.C. (2006).
The AddAB helicase/nuclease forms a stable complex with its cognate chi sequence during translocation.
J. Biol. Chem., 281, 18610-18617. PMID: 16632468. (published online April 21, 2006 as doi:10.1074/jbc.M600882200). 
[Abstract] [Full Text] [PDF]