Kowalczykowski, Stephen




B.S., Chemistry, 1972 - Rensselaer Polytechnic Institute

Ph. D, Chemistry (Biochemistry), 1976 - Georgetown University

Postdoctoral Fellow, Molecular Biology, 1981 - University of Oregon

Graduate Group Membership:

Biochemistry, Molecular, Cellular and Developmental Biology

Faculty Appointments:

Department of Microbiology & Molecular Genetics
Department of Molecular & Cellular Biology

Stephen Charles Kowalczykowski                     (CV-pdf)
Distinguished Professor of Microbiology & Molecular Genetics, and of Molecular & Cellular Biology
Briggs Hall - 310
University of California, Davis
Davis, CA 95616-8665

PHONE:     530-752-5938
FAX:            530-752-5939
E-MAIL:      sckowalczykowski@ucdavis.edu


Rensselaer Polytechnic Institute, Troy, New York, B.S., Chemistry, 1972
Senior Thesis Research with Dr. Frederick Wedler
Topic:     "Substrate Binding Order of Sheep Brain Glutamine Synthetase"

Georgetown University, Washington, D.C., Ph. D., Chemistry (Biochemistry), 1976
Doctoral Thesis Research with Dr. Jacinto Steinhardt
Topic:     "Physical-Chemical Studies of Sickle Cell Hemoglobin"

University of Oregon, Eugene, Oregon, Postdoctoral, Molecular Biology, 1981
American Cancer Society Postdoctoral Fellow with Dr. Peter von Hippel
Topic:     "Interactions of Bacteriophage T4-Coded Gene 32 Protein with Nucleic Acids"

Northwestern University Medical School, Chicago, Illinois (1981-1991)
Assistant Professor of Molecular Biology, (1981-1987)
Associate Professor of Molecular Biology, (1987-1991)
Topics:    "Mechanistic Studies of Genetic Recombination";
                 "Biochemical Mechanism and Function of DNA Helicases"

University of California, Davis, Davis, California (1991- present)
Professor of Microbiology and of Molecular Biology and Cell Biology, (1991-present)
Chairman, Section of Microbiology (1992-1999)
Director, Center for Genetics and Development (2000-present)
Topics:    "Mechanistic Studies of Genetic Recombination";
                 "Biochemical Mechanism and Function of DNA Helicases"
                 "Recombinational Repair of DNA Damage in Eukaryotes"
"Single-Molecule Assembly of Protein-DNA complexes"
Molecular Etiology of Cancer"


Rensselaer Polytechnic Institute Scholarship, 1968-1972
Phi Lambda Upsilon, Chemical Honor Society, 1971
Georgetown University Fellowship, 1972-1976
Sigma Xi, 1974
American Cancer Society Postdoctoral Fellowship, 1977-1980
American Cancer Society Junior Faculty Research Award, 1983-1986
Roll of Honour of Polish Science, 2000
National Institutes of Health MERIT Award, 2000-2010
American Association for the Advancement of Science, Fellow, 2001
American Academy of Microbiology, Fellow, 2003
(UC Davis News & Information - printable)
University of California, Davis, Academic Senate, Faculty Distinguished Research Award, 2005
American Academy of Arts & Sciences, Fellow, 2005
National Academy of Sciences, Member, 2007
University of California, Davis, College of Biological Sciences, Faculty Research Award, 2011
Michael J. Gait Award, Nucleic Acids Group of the Royal Society of Chemistry, 2012 (Newsletter)


American Chemical Society, Division of Biological Chemistry, 1972
American Association for the Advancement of Sciences, 1975
American Society for Biochemistry and Molecular Biology, FASEB, 1985
Biophysical Society, 1980
American Society for Microbiology, 1991


Associate Editor, Genes to Cells (1995-present)
Faculty of 1000 (2001-2005)
Editorial Board, The Journal of Biological Chemistry (2003-2008)
Editorial Board, Journal of Bacteriology (2004-2006)
Editorial Advisory Board, ACS Chemical Biology (2006-2008)
Editorial Board, Proceedings of the National Academy of Sciences (2008-2015)
Editorial Board, DNA Repair (2009-present)
Editorial Board, Journal of Molecular Biology (2012-2015)


National Institutes of Health; 2R01 GM-62653-34
"Mechanistic Studies of Genetic Recombination"
Impact/priority score: 26; percentile 8.0%
7/14 3/18; Direct Costs - $1,344,230; Total Costs - $2,065,814

National Institutes of Health; 5R01 GM-64745-11
"Single-Molecule Assembly of Protein-DNA complexes"
Impact/priority score: 10; percentile 2%
7/11 6/15; Direct Costs - $820,000; Total Costs - $1,259,725

National Institutes of Health; 5R01 CA154920-04 (co-PI with Heyer)
"Functions of Rad51 Paralogs in Recombinational DNA Repair"
Impact/priority score: 10; percentile 1.0%
9/11 7/16; Direct Costs - $1,771,252; Total Costs - $2,726,181

National Institutes of Health; 5R01 GM-41347-25
"Biochemical Mechanisms and Function of DNA Helicases"
Impact/priority score: 20; percentile 6.0%
4/12 4/17; Direct Costs - $1,269,974; Total Costs - $1,885,126

Department of Defense; W81XWH-13-1-0322
"Biological Function of Human BRCA2 in the Molecular Etiology of Breast Cancer"
9/13 - 9/15; Direct Costs - $371,886; Total Costs - $577,086


                    View my collection, "My Bibliography" from NCBI


Davis  Community Television: Get The Word Out - "Double helix unwinds on camera."  [VIDEO]
Stephen Kowalczykowski interviewed by Jon Price
February 8, 2001 7:00 PM (Rerun on Tues Feb 13, 2001 at 7:30 PM)

PROFILE: "Nanotech Dreams" - The Scientist 16[5]:34, Mar. 4, 2002 - (excerpt) [Full article]

"Highly cited paper" selected by ISI Essential Science Indicators (2002): "This paper ranks among the top 15 highly cited papers in the field of Microbiology", "in-cites", April, 2002  (http://www.in-cites.com/BI-april2002.html ):
Biochemistry of homologous recombination in Escherichia coli.
Kowalczykowski, S.C., Dixon, D.A., Eggleston, A.K., Lauder, S.D., and Rehrauer, W.M. (1994).
Microbiol. Rev., 58, 401-465. PMID: 7968921; PMCID: PMC372975. [Abstract] [Full Text] [PDF]
Read interview with Dr. Stephen Kowalczykowski

NIH Videocasting: DNA Repair Interest Group
Biochemistry of Recombinational DNA Repair: Common Themes  [Download Video]
Author: Dr. Steve Kowalczykowski, UC Davis
Tuesday, January 20, 2004; Total Running Time: 01:22:39; NLM ID: 101268343
Slide Show  or  PDF Presentation

                    KITP Program: New Physical Approaches to Molecular and Cellular Machines (Apr 3 - Jun 30, 2006)
Visualization of Protein-DNA Complexes at the Single-Molecule Level  [Video-QuickTime] [Video-Real Player] [Podcast]
                    Dr. Stephen Kowalczykowski, UC Davis