2015

 

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Fasching, C.L., Cejka, P., Kowalczykowski, S.C., and Heyer, W.D. (2015)
Top3-rmi1 dissolve rad51-mediated d loops by a topoisomerase-based mechanism.
Mol. Cell. 57
, 595-606 (published online February 19, 2015 as doi:
10.1016/j.molcel.2015.01.022). PMID: 25699708; PMCID: PMC4338411. [Abstract] [Full Text] [PDF] [SupplementaI Information]

Chen, H., Donnianni, R.A., Handa, N., Deng, S.K., Oh, J., Timashev, L.A., Kowalczykowski, S.C., and Symington, L.S. (2015)
Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.
Proc. Natl. Acad. Sci.
(published online March 23, 2015 as pii:201503331). PMID: 25831494; PMCID: PMC4403154. [Abstract] [Full Text] [PDF] [Supporting Information]

Lee, K.Y., Im, J.S., Shibata, E., Park, J., Handa, N., Kowalczykowski, S.C., and Dutta, A. (2015)
MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.
Nat. Commun.
(published online July 28, 2015, 10.1038/ncomms8744). PMID: 26215093; PMCID: PMC4525285. [Abstract] [Full Text] [PDF] [Supplementary Information]

Wang, A.T., Kim, T., Wagner, J.E., Conti, B.A., Lach, F.P., Huang, A.L., Molina, H., Sanborn, E.M., Zierhut, H., Cornes, B.K., Abhyankar, A., Sougnez, C., Gabriel, S.B., Auerbach, A.D., Kowalczykowski, S.C., and Smogorzewska, A. (2015)
A dominant mutation in human RAD51 reveals its function in DNA interstrand crosslink repair independent of homologous recombination.
Mol. Cell. 59
, 478-490 (published online August 6, 2015 as doi: 10.1016/j.molcel.2015.07.009). PMID: 26253028; PMCID: PMC4529964. [Abstract] [Full Text] [PDF]

Bell, J.C., Liu, B., and Kowalczykowski, S.C. (2015)
Imaging and energetics of single SSB-ssDNA molecules reveal intramolecular condensation and insight into RecOR function.
Elife
, (published online September 18, 2015 as doi: 10.7554/eLife.08646). PMID: 26381353: PMCID: PMC4652220. [Abstract] [Full Text] [PDF]

Kowalczykowski, S.C. (2015)
An overview of the molecular mechanisms of recombinational DNA repair.
Cold Spring Harb. Perspect. Biol. 7
, (published online November 2, 2015 as pii: a016410. doi: 10.1101/cshperspect.a016410). PMID: 26525148; PMCID: PMC4632670. [Abstract] [Full Text] [PDF]

Rad, B., Forget, A.L., Baskin, R.J., and Kowalczykowski, S.C. (2015)
Single-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding.
Proc. Natl. Acad. Sci. USA 112, E6852-6861
(published online November 4, 2015 as doi: 10.1073/pnas.1518028112). PMID: 26540728; PMCID: PMC4687592. [Abstract] [Full Text] [PDF] [Supporting Information]