Bell, Jason

 

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Jason Corey Bell

B.S., 2004, Biochemistry - Louisiana State University, Baton Rouge, Louisiana

Ph.D., 2011, Biochemistry and Molecular Biology - University of California, Davis, California

Postdoctoral Researcher, 2013-2014, University of California, Davis, CA
  Current Address:

Postdoctoral Scholar - Straight Lab
Department of Biochemistry
Stanford University
Beckman Center, B400
279 West Campus Drive
Stanford, CA 94305-1234
jcbell@stanford.edu

Bell, J.C.
Dynamic assembly of RecA filaments on single molecules of SSB-coated ssDNA
Ph. D. Thesis, University of California at Davis, 2011.

Dillingham, M.S., Tibbles, K.L., Hunter, J.L., Bell, J.C., Kowalczykowski, S.C., and Webb, M.R. (2008).
Fluorescent single-stranded DNA binding protein as a probe for sensitive, real-time assays of helicase activity.
Biophys. J., 95
, 3330-3339
(published online July 3, 2008, as 10.1529/biophysj.108.133512). PMID: 18599625; PMCID: PMC2547451 [Abstract] [Full Text] [PDF]

Bell, J.C., Plank, J.L., Dombrowski, C.C., and Kowalczykowski, S.C. (2012)
Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA.
Nature,
491, 274-278 (published online 24 October 2012 as doi: 10.1038/nature11598). PMID
: 23103864; PMCID: PMC4112059. [Abstract] [Full Text] [PDF] [Supplementary Information] [Video 1: Direct imaging of nucleation and growth of RecA on SSB-coated ssDNA] [Video 2: Optical trapping and manipulation of single molecules of gapped DNA for direct imaging of RecAf filament assembly]
(see Nature News & Views: A glimpse of molecular competition [PDF])
(see Phys.org News: Single-DNA images give clues to breast cancer [PDF])
(see Scientific Blogging: Rad51: Watching single strands of DNA being prepped for repair could help fight breast cancer  [Printable] [PDF])
(see UC Davis News and Information: Single-DNA images give clues to breast cancer  [Video] [PDF])
Access the recommendation on F1000Prime

Bell, J.C., Liu, B., and Kowalczykowski, S.C. (2015)
Imaging and energetics of single SSB-ssDNA molecules reveal intramolecular condensation and insight into RecOR function.
Elife
, (published online September 18, 2015 as doi: 10.7554/eLife.08646). PMID: 26381353. [Abstract] [Full Text] [PDF]

Bell, J.C. and Kowalczykowski, S.C. (2016)
Mechanics and single-molecule interrogation of DNA recombination.
Annu. Rev. Biochem.
, Epub ahead of print, April 18, 2016. PMID: 27088880. [Abstract] [Full Text] [PDF] [Supplemental Materials]