Jensen, Ryan

 

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Ryan Jensen

B.A., 1996, Molecular & Cellular Biology (Emphasis:  Biochemistry) - University of California, Berkeley, CA

Ph.D., 2004, Genetics - Yale University School of Medicine, New Haven, CT

1996-1998, Sugen, Inc., South San Francisco, CA.  Research.

1998-1999, Stanford University, Palo Alto, CA. Research Assistant.

1999-2004, Yale University School of Medicine, New Haven, CT.

2004-2010, University of California at Davis, Davis, CA.   American Cancer  Society Postdoctoral Fellow.

2010-2011, University of California at Davis, Davis, CA. Project Scientist.

  Current address:

Assistant Professor
Yale School of Medicine
333 Cedar Street
New Haven, CT 06510
Tel: (203) 737-6456
ryan.jensen@yale.edu

Hoppe, B.S., Jensen, R.B., and Kirchgessner, C.U. (2000).
Complementation of the radiosensitive M059J cell line.
Radiat. Res. 153
, 125-30.

Peretz, S., Jensen, R., Baserga, R., and Glazer, P.M. (2001).
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response.
Proc. Natl. Acad. Sci. (USA) 98
,1676-81.

Mihaylova, V.T., Bindra, R.S., Yuan, J., Campisi, D., Narayanan, L., Jensen, R., Giordano, F., Johnson, R.S., Rockwell, S., and Glazer, P.M. (2003).
Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.
Mol. Cell. Biol. 23
, 3265-73.

Jensen, R. and Glazer, P.M. (2004).
Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced through gap junctions.
Proc. Natl. Acad. Sci. (USA) 101
, 6134-6139.

Jensen, R.B., Carreira, A., and Kowalczykowski, S.C. (2010)
Purified human BRCA2 stimulates RAD51-mediated recombination.
Nature,
467, 678-683 (published online: August 22, 2010, doi: 10.1038/nature09399). PMID: 20729832; PMCID: PMC2952063  [Abstract] [Full Text] [PDF] [Supplementary Information]

(see UC Davis interview: [Video-Flash] [Video-MPEG4])
(see Nature News & Views: DNA Repair: A protein giant in its entirety [PDF])
(see Nature News: Breast cancer protein is finally purified Latest News [PDF])
(see American Cancer Society News: New finding may unlock secrets of BRCA mutations [PDF])
(see Biocompare, Life Sciences Articles, News: Protein made by breast cancer gene purified [PDF])
(see Biomedical Beat - National Institute of General Medical Sciences: BRCA2 Breakthrough  News [PDF])
(see Bionity.com: Protein made by breast cancer gene purified [PDF])
(see BioTechniques: New gels shed light on cancer-related protein [PDF])
(see Congressionally Directed Medical Research Programs (CDMRP), Breast Cancer Research Highlights: Successful isolation of BRCA2 (breast cancer type 2 susceptibility protein) and elucidation of its mechanistic functions underlying breast cancer tumorigenesis [PDF])
(see Davis Enterprise: Scientists dig into breast cancer origins [PDF])
(see Deutsches Ärzteblatt:
Brustkrebs-Protein im Labor hergestellt [PDF])
(see e! Science News: Protein made by breast cancer gene purified [PDF])
(see ebiotrade: "Nature": successfully isolated and purified human lung cancer gene BRCA2 protein [PDF])
(see Eurekalert.org: Protein made by breast cancer gene purified [PDF])
(see GENNewsHighlights: Researchers succeed in purifying protein expressed by BRCA2 [PDF])
(see GenomeWeb: The elusive protein, found [PDF])
(see Guttenberg Municipal Hospital, HealthDay Daily Newsfeed: Inner workings of gene tied to breast, ovarian cancer revealed [PDF])
(see Higher Colleges of Technology, HCT Libraries: BRCA2, purified, reveals some of its secrets [PDF])
(see The Hindu: Protein made by breast cancer gene 'purified' [PDF])
(see Innovations Report: Protein made by breast cancer gene purified [PDF])
(see Journal of the National Cancer Institute: BRCA2, purified, reveals some of its secrets [PDF])
(see Justmeans: New finding may unlock secrets of BRCA mutations [PDF])
(see Lahey Hospital and Medical Center, HealthDay News: Inner workings of gene tied to breast, ovarian cancer revealed [PDF])
(see Mammary Cell News: Breast cancer protein is finally purified [PDF])
(see MedGuru: Pure form of tumor protein extracted successfully [PDF])
(see Medical News Today: Purification of protein made by breast cancer gene [PDF])
(see medwireNews: Purification of BRCA2 protein allows understanding of its role in DNA repair [PDF])
(see ModernMedicine: Researchers isolate BRCA2 protein for first time [PDF])
(see MSN Health and Fitness: Inner workings of
gene tied to breast, ovarian cancer revealed [PDF])
(see Natureasia.com: BRCA2 protein characterized [PDF])
(see News, Chauthi Duniya: Breast-cancer protein purified [PDF])
(see NewScientist Health: Fundamental breast and ovarian cancer protein isolated [PDF])
(see Pharmaceutical Online: Protein made by breast cancer gene purified [PDF])
(see Santa Maria Law: Breast cancer research [PDF])
(see Science Codex: Protein made by breast cancer gene purified [PDF])
(see ScienceDaily: Protein made by breast cancer gene purified [PDF])
(see Softpedia News: Breast cancer protein scrutinized [PDF])
(see Synthesis, Fall/Winter 2010: Protein made by breast cancer gene purified [PDF])
(see Synthesis, Spring/Summer 2011: Solving a genetic puzzle: Major findings open doors in DNA repair research [PDF])
(see USNews Health: Inner workings of gene tied to breast, ovarian cancer revealed [PDF])
(see UC Davis Health System News: Protein made by breast cancer gene purified [PDF])
(see UC Davis News & Information: Protein made by breast cancer gene purified [PDF] [printable])
(see WSFA 12 News Montgomery, AL: Inner workings of gene tied to breast, ovarian cancer revealed [PDF])
(see Yahoo! Movies India: Breast-cancer protein purified [PDF])

Jensen, R.B., Ozes, A., Kim, T., Estep, A., and Kowalczykowski, S.C. (2013)
BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage.
DNA Repair, 12,
306-311. PMID: 23384538; PMCID: PMC3602134. [Abstract] [Full Text] [PDF] [Supplementary Figure I] [Supplementary Figure II] [Supplementary Figure III]

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