Anderson, Daniel

 

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Dan Anderson.jpg (47648 bytes) Daniel G. Anderson

B.A., Biology, Mathematics, 1992 - University of California, Santa Cruz

M.S., Genetics, 1995 - University of California, Davis

Ph.D., Genetics, 1997 - University of California, Davis

  Current address:

Associate Professor
Department of Chemical Engineering
Massachusetts Institute of Technology
Room 76-653F
77 Massachusetts Avenue
Cambridge, MA 02139
Office Tel: (617) 258-6843
Fax (617) 258-8827
email:
dgander@mit.edu

Anderson, D.G. and Kowalczykowski, S.C. (1997).
The recombination hot spot chi is a regulatory element that switches the polarity of DNA degradation by the RecBCD enzyme.
Genes & Dev., 11, 571-581. PMID: 9119222. [Abstract] [Full Text] [PDF]

Anderson, D.G., Churchill, J.J., and Kowalczykowski, S.C. (1997).
Chi-activated RecBCD enzyme possesses 5' 3' nucleolytic activity, but RecBC enzyme does not: Evidence suggesting that the alteration induced by Chi is not simply ejection of the RecD subunit.
Genes to Cells, 2, 117-128. PMID: 9167969. [Abstract] [PDF]

Anderson, D.G. and Kowalczykowski, S.C. (1997).
The translocating RecBCD enzyme stimulates recombination by directing RecA protein onto ssDNA in a c-regulated manner.
Cell, 90, 77-86. PMID: 9230304. [Abstract] [Full Text] [PDF]
(see Dispatch in Current Biology:  [Full Text] [PDF]

Anderson, D.G. and Kowalczykowski, S.C. (1998).
SSB protein controls RecBCD enzyme nuclease activity during unwinding: A new role for looped intermediates.
J. Mol. Biol., 282, 275-285. PMID: 9735287. [Abstract] [Full Text] [PDF]

Anderson, D.G. and Kowalczykowski, S.C. (1998).
Reconstitution of an SOS response pathway: derepression of transcription in response to DNA breaks.
Cell, 95, 975-979. PMID: 9875851. [Abstract] [Full Text] [PDF]

Churchill, J.J., Anderson, D.G., and Kowalczykowski, S.C. (1999).
The RecBC enzyme loads RecA protein onto ssDNA asymmetrically and independently of c, resulting in constitutive recombination activation.
Genes & Dev. 13, 901-911. PMID: 10197989, PMCID: PMC316600. [Abstract] [Full Text] [PDF]

Anderson, D.G., Churchill, J.J., Kowalczykowski, S.C. (1999).
A single mutation, RecBD1080A, eliminates RecA protein loading but not Chi recognition by RecBCD enzyme.
J. Biol. Chem., 274, 27139-27144. PMID: 10480929.
[Abstract] [Full Text] [PDF]