Publications › Privalsky


Alternative mRNA Splicing of Corepressors Generates Variants That Play Opposing Roles in Adipocyte Differentiation.
Goodson ML, Mengeling BJ, Jonas BA, Privalsky ML.
Journal of Biological Chemistry, 2011 Dec 30; 286(52):44988-99. doi:10.1074/jbc.M111.291625
PMID:22065574 PMCID:PMC3247966

Mutant Thyroid Hormone Receptors (TRs) Isolated from Distinct Cancer Types Display Distinct Target Gene Specificities: A Unique Regulatory Repertoire Associated with Two Renal Clear Cell Carcinomas.
Rosen MD, Chan IH, Privalsky ML.
Molecular Endocrinology, 2011 Aug; 25(8):1311-25. doi:10.1210/me.2010-0420
PMID:21622534 PMCID:PMC3146248

A Mechanism for Pituitary-Resistance to Thyroid Hormone (PRTH) Syndrome: a Loss in Cooperative Coactivator Contacts by Thyroid Hormone Receptor (TR)β2.
Lee S, Young BM, Wan W, Chan IH, Privalsky ML.
Molecular Endocrinology. 2011 Jul;25(7):1111-25. doi: 10.1210/me.2010-0448.
PMID:21622532 PMCID:PMC3125096

NCoR1 regulates thyroid hormone receptor isoform-dependent adipogenesis.
Zhu XG, Kim DW, Goodson ML, Privalsky ML, Cheng SY.
Journal of Molecular Endocrinology, 2011 Jun 9; 46(3):233-44. doi:10.1530/JME-10-0163
PMID:21389087 PMCID:PMC3457783

Thyroid Hormone Receptor Mutations in Cancer and Resistance to Thyroid Hormone: Perspective and Prognosis.
Rosen MD, Privalsky ML.
Journal of Thyroid Research, 2011; 2011:361304. doi:10.4061/2011/361304
PMID:21760978 PMCID:PMC3134260

Aberrant Corepressor Interactions Implicated in PML-RARα and PLZF-RARα Leukemogenesis Reflect an Altered Recruitment and Release of Specific NCoR and SMRT Splice Variants.
Mengeling BJ, Phan TQ, Goodson ML, Privalsky ML.
Journal of Biological Chemistry, 2011 Feb 11; 286(6):4236-47. doi:10.1074/jbc.M110.200964
PMID:21131350 PMCID:PMC3039402

Regulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation.
Varlakhanova N, Hahm JB, Privalsky ML.
Molecular and Cellular Endocrinology, 2011 Jan 30; 332(1-2):180-8. doi:10.1016/j.mce.2010.10.010
PMID:20965228 PMCID:PMC3011023

Nuclear receptor coregulators as a new paradigm for therapeutic targeting.
Hsia EY, Goodson ML, Zou JX, Privalsky ML, Chen HW.
Advanced Drug Delivery Reviews, 2010 Oct 30; 62(13):1227-37. doi:10.1016/j.addr.2010.09.016