2009

 

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Hilario, J., Amitani, I., Baskin, R.J., and Kowalczykowski, S.C. (2009)
Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules.

Proc. Natl. Acad. Sci. U.S.A., 106
, 361-368 (published online January 2, 2009, doi: 10.1073/pnas.0811965106.) PMID: 19122145; PMCID: PMC2613362
[Abstract] [Full Text] [PDF] [Supporting Information] [Movie 1] [Movie 2] [Movie 3]
(see About Medicine: Fluorescent microscopy captures the repair protein Rad51 as it assembles into a filament on DNA [PDF])
(see Biocompare News: Human DNA repair process recorded in action [PDF])
(see Biology News Net: Human DNA repair process recorded in action [PDF])
(see Biophotonics: Mending broken DNA [PDF])

(see e! Science News: Human DNA repair process recorded in action [PDF])
(see EurekAlert: Human DNA repair process recorded in action [PDF])
(see Insciences Organisation: Human DNA repair process recorded in action [PDF])

(see Machines Like Us, News: Human DNA repair process recorded in action [PDF])
(see MacNewsWorld: EurekAlert: Human DNA repair process recorded in action [PDF])
(see Medical News Today: Fluorescent microscopy captures the repair protein Rad51 as it assembles into a filament on DNA [PDF])
(see Newsguide.us: Human DNA repair process recorded in action [PDF])
(see Newsweek, National News: Human DNA repair process recorded in action (Video) [PDF])
(see Overwhelming Evidence: Human DNA repair process video - by chance? [PDF])
(see Phys.org/News: Human DNA repair process recorded in action (Video) [PDF])
(see ScienceBlog: Human DNA repair process recorded in action [PDF])
(see Science Codex: Human DNA repair process recorded in action [PDF])
(see Science Daily: Human DNA repair process recorded in action [PDF])
(see ScienceMode.com: Human DNA repair process recorded in action [PDF])
(see The Sensuous Curmudgeon: Human DNA repair process recorded [PDF])
(see UCDavis News and Information: Human DNA repair process recorded in action Caught in the act: Our DNA under repair  [Video] [Printable])
(see Uncommon Descent: Human DNA repair process video - by chance? [PDF])

Nimonkar, A.V., Sica, R.A., and Kowalczykowski, S.C. (2009)
Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules.
Proc. Natl. Acad. Sci. U.S.A., 106, 3077-3082 (published online February 9, 2009, doi:10.1073/pnas.0813247106).  PMID: 19204284; PMCID: PMC2651264 [Abstract] [Full Text] [PDF] [Supporting Information]

Haseltine, C. A. and Kowalczykowski, S.C. (2009)
An archaeal Rad54 protein remodels DNA and stimulates DNA strand exchange by RadA.
Nucl. Acids Res., 37,
2757-2770. (published online March 12, 2009, doi:10.1093/nar/gkp068). PMID: 19282450; PMCID: PMC2677860
[Abstract] [Full Text] [PDF]

Carreira, A., Hilario, J., Amitani, I., Baskin, R.J., Shivji, M.K.K., Venkitaraman, A.R., and Kowalczykowski, S.C. (2009)
The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51.

Cell, 136,
1032-1043, (doi:10.1016/j.cell.2009.02.019). PMID: 19303847; PMCID: PMC2669112  [Abstract] [Full Text] [PDF] [Supplemental Data]
(see Cell, In this Issue: BRCA2 Focuses RAD51 for Repair  [PDF])
Access the recommendation on F1000Prime

Handa, N., Morimatsu, K., Lovett, S.T., and Kowalczykowski, S.C. (2009)
Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli.
Genes & Dev.,
23, 1234-1245. PMID: 19451222; PMCID: PMC2685532 
[Abstract] [Full Text] [PDF] [Supplemental Material]
(see Current Biology Dispatch: DNA Repair: Common Approaches to Fixing Double-Strand Breaks [PDF])
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Handa, N., Amitani, I., Gumlaw, N., Sandler, S.J., and Kowalczykowski, S.C. (2009)
Single molecule analysis of a red fluorescent RecA Protein reveals a defect in nucleoprotein filament nucleation that relates to its reduced biological functions.
J. Biol. Chem.,
284, 18664-73 (published online May 5, 2009, doi:10.1074/jbc.M109.004895). PMID: 19419960; PMCID: PMC2707236 
[Abstract] [Full Text] [PDF]

Nimonkar, A.V. and Kowalczykowski, S.C. (2009)
Second-end DNA capture in double-strand break repair: How to catch a DNA by its tail.

Cell Cycle, 8
, 1816-1817. PMID: 19471119; PMCID: PMC3051008. [Full Text] [PDF]

Carreira, A. and Kowalczykowski, S.C. (2009)
BRCA2: Shining light on the regulation of DNA-binding selectivity by RAD51.
Cell Cycle,
21, 11-13. PMID: 19838057; PMCID: PMC3050000. [Full Text] [PDF]