PUBLICATIONS
Sasanuma, H., Tawaramoto, M.S., Lao, J.P., Hosaka, H., Sanda, E., Suzuki, M., Yamashita, E., Hunter, N., Shinohara, A., A. Nakagawa, A., Shinohara, A. (2013). A new protein complex promoting the assembly of Rad51 filaments. Nature Communications doi: 10.1038/ncomms2678. Link
Reynolds, A., Qiao, H., Yang, Y., Chen, J., Biswas, K., Holloway, K., Baudat, F., de Massy, B., Wang. J., Höög, C., Cohen, P. and Hunter, N. (2013). RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis. Nature Genetics 45, 269-78. Link
News & Views
Biswas, K., Das, R., Eggington, J.M., Qiao, H., North, S.L., Stauffer, S., Burkett, S., Betty K. Martin, B.S., Southon, E, Sizemore, S.C., Pruss, D., Bowles, K.R., Roa, B.B., Hunter, N., Tessarollo, L., Wenstrup, R.J., Byrd, R.A. and Sharan, S.K. (2012). Functional evaluation of BRCA2 variants mapping to the PALB2 binding and C-terminal DNA binding domains using a mouse ES cell–based assay. Human Molecular Genetics 21, 3993-4006. Link
Qiao H., Chen, J., Reynolds, A., Höög, C., Paddy, M. and Hunter, N. (2012). Interplay between centromeres, synaptonemal complex and homologous recombination during mammalian meiosis. PLoS Genetics, PLoS Genet 8(6): e1002790. doi:10.1371/journal.pgen.1002790. Link
Perspective
Lao, J.P., Tang, S. and Hunter, N. (2012). Native/Denaturing Two-Dimensional DNA Electrophoresis And Its Application To The Analysis Of Recombination Intermediates. In, Methods in Molecular Biology, DNA Electrophoresis: Methods and Protocols (Totowa, Humana Press).
Zakheryevich, K, Tang, S., Ma, Y. and Hunter, N. (2012). Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase. Cell, 49 334-347. PubMed
Preview
Hunter, N. (2011). Double Duty For Exo1 During Meiotic Recombination. Cell Cycle 10(16), 2607-2609. PubMed
Hwang, Y-H. and Hunter, N. (2011). Mapping meiotic breaks: Spo11 oligonucleotides precisely mark the spots. Genome Biology 12, 111-114. doi:10.1186/gb-2011-12-4-111. PubMed
Zakheryevich, K, Ma, Y., Tang, S., Hwang, Y-H., Boiteux, S. and Hunter, N. (2010). Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand-break resection and resolution of double-Holliday Junctions. Molecular Cell, 40, 1001-1015. PubMed
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Hunter, N. (2010). Meiosis. In, The Encyclopedia of Biological Chemistry 2nd Edition, Lennarz, W. and Lane, M. (Eds), Elsevier Press, San Diego, In press.
Lao, J.P. and Hunter, N. (2010). Trying to Avoid Your Sister. PLoS Biology, 8(10): e1000519. PubMed
Bzymek, M., Thayer, N.H., Oh, S.D., Kleckner, N. and Hunter, N. (2010). Double-Holliday Junctions are Intermediates of DNA Break Repair. Nature 464, 937-941. Pubmed
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Oh S.D., Jessop, L., Lao, J.P., Lichten, M.J. and Hunter, N.H. (2009). Stabilization and Electrophoretic Analysis of Meiotic Recombination Intermediates in Saccharomyces cerevisiae. In, Methods in Molecular Biology, Meiosis Methods and Protocols, Scott Keeney, ed. (Totowa, Human Press). Link
Oh S.D., Lao, J.P. and Hunter, N. (2008). RecQ Helicase, Sgs1, and XPF-Family Endonuclease, Mus81-Mms4, Resolve Aberrant Joint Molecules During Meiotic Recombination. Molecular Cell 31, 324-336. PubMed
Hunter, N. (2008). Hop1 and the meiotic DNA-damage response. Cell 132, 731-732. PubMed
Hunter, N. (2008). The RecQ DNA helicases: Jacks-of all-trades or master-tradesmen? Cell Research 18, 328-330. PubMed
Shinohara, M, Oh, S.D., Hunter, N. and Shinohara, A. (2008). Crossover assurance and crossover interference are distinctly regulated by the ZMM/SIC proteins during meiosis. Nature Genetics 40, 299-309. PubMed
News & Views
Lao, J.P, Oh, S.D., Shinohara, M., Shinohara, A. and Hunter, N. (2008). Rad52 promotes post-invasion steps of meiotic double-strand-break repair. Molecular Cell 29, 517–524. PubMed
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Oh S.D., Lao, J.P., Hwang, P.Y-H., Taylor, A.F., Smith, G.R. and Hunter, N. (2007). BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing the formation of multi-chromatid joint molecules. Cell 130, 259-272. PubMed
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Hunter, N. (2006). Meiotic Recombination. In, Topics in Current Genetics, Molecular Genetics of Recombination, Aguilera, A. and Rothstein, R. (Eds), Springer-Verlag, Heidelberg, pp. 381-442. Link
Cromie, G. A., Hyppa, R. W., Taylor, A. F., Zakharyevich, K., Hunter, N., and Smith, G. R. (2006). Single Holliday Junctions are intermediates of meiotic recombination. Cell 127, 1167-1178. PubMed
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Martini, E., Diaz, R.L., Hunter, N. and Keeney, S. (2006). Crossover homeostasis in yeast meiosis. Cell 126, 285-295.
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McDougall, A., Elliot, D.J. and Hunter, N. (2005). Pairing, connecting, exchanging, pausing and pulling chromosomes: Meeting on the cell-cycle regulation of meiosis. EMBO Reports, 6, 120-125. PubMed
Hunter, N. (2004). Meiosis. In, The Encyclopedia of Biological Chemistry, 1st Edition, Lennarz, W. and Lane, M. (Eds), Elsevier Press, San Diego, pp. 610-616. Link
Börner, V.G., Kleckner, N. and Hunter, N. (2004). Crossover/noncrossover differentiation, synaptonemal complex formation and regulatory surveillance at the leptotene/zygotene transition of meiosis. Cell 117, 29-45. PubMed
Review Highlighted by Faculty of 1000 Biology
Hunter, N. (2003). Synaptonemal complexities and commonalities. Molecular Cell, 12, 533-535. PubMed
de los Santos, T., Hunter, N., Lee, C., Larkin, B., Loidl, J., and Hollingsworth, N.M. (2003). The Mus81/Mms4 endonuclease acts independently of double-Holliday junction resolution to promote a distinct subset of crossovers during meiosis in budding yeast. Genetics, 164, 81-94. PubMed Highlighted by Faculty of 1000 Biology
Blat, Y., Protacio, R., Hunter, N. and Kleckner, N. (2002). Physical and functional interactions among basic chromosome organizational features govern early steps of meiotic chiasma formation. Cell, 111, 791-802. PubMed
Hunter, N. and Kleckner, N. (2001). The single-end invasion: an asymmetric intermediate at the double-strand-break to double-Holliday junction transition of meiotic recombination. Cell, 106, 59-70. PubMed
Hunter, N., Börner, G.V., Lichten, M. and Kleckner, N. (2001). gamma-H2AX illuminates meiosis. Nature Genetics, 27, 236-238. PubMed
Wang, T.F., Kleckner, N. and Hunter, N. (1999). Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A, 96, 13914-13919. PubMed Comment
Hunter, N. and Borts, R.H. (1997). Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosis. Genes Dev, 11, 1573-1582. PubMed
Chambers, S.R., Hunter, N., Louis, E.J. and Borts, R.H. (1996). The mismatch repair system reduces meiotic homeologous recombination and stimulates recombination-dependent chromosome loss. Mol Cell Biol, 16, 6110-6120. PubMed
Hunter, N., Chambers, S.R., Louis, E.J. and Borts, R.H. (1996). The mismatch repair system contributes to meiotic sterility in an interspecific yeast hybrid. EMBO J, 15, 1726-1733. PubMed
Nemeth, A.H., Hunter, N., Coleman, M.P., Borts, R.H., Louis, E.J. and Davies, K.E. (1993). Rescue of a single yeast artificial chromosome from a cotransformation event utilizing segregation at meiosis. Genet Anal Tech Appl, 10, 123-127. PubMed