Jie Liu

Jie

E-mail: jtliu@ucdavis.edu

Cellular and molecular mechanisms of S. cerevisiae Rad55-Rad57 proteins.

Scientific interests

Homologous recombination, DNA repair, and cancer research.

Education

1995-1999         Wuhan University                      B.S.                  Biochemistry
2000-2006       University of Vermont              Ph.D.               Biochemistry

Work experience

Protein biochemistry, nucleic acid-protein interactions, fluorescence, and enzyme kinetics.

Honors and awards

2005                Keystone Symposia Fellowship, Keystone Symposia, Keystone, CO
2005                Workshop Oral Presenter (January 6th), Keystone Symposium on
Mechanisms of DNA Replication and Recombination, Keystone, CO
2003                DOE-EPSCoR Predoctoral Fellowship in Structural Biology

Publications

1. Liu, J., Renault, L., Veaute, X., Fabre, F., Stahlberg, H. & W.-D. Heyer (2011) Rad51 paralogues Rad55–Rad57 balance the antirecombinase Srs2 in Rad51 filament formation. Nature 479: 245–248 [PDF]

2. Liu, J., Sneeden, J. and W.-D. Heyer (2011) In Vitro Assays for DNA pairing and recombination-associated DNA synthesis in H. Tsubouchi (ed.), DNA Recombination, Methods Mol Biol. 745:363-83.

3. Liu, J., Ehmsen, K. T., Heyer, W.-D. and S. W. Morrical (2011) Presynaptic filament dynamics in homologous recombination and DNA repair. Crit Rev Biochem Mol Biol. 2011 Jun;46(3):240-70.

4. Liu, J. and W.-D. Heyer (2011) Who’s who in human recombination: BRCA2 and RAD52
PNAS. 2011; 108:441-442 [PDF]

5. Heyer, W.-D., Ehmsen, K. and Liu, J. (2010) Regulation of Homologous Recombination in Eukaryotes Annu Rev Genet. 44: 113-139 [PDF]

6. Liu, J., Qian, N., & Morrical, S.W. (2006), Dynamics of Bacteriophage T4 Presynaptic Filament Assembly from Extrinsic Fluorescence Measurements of Gp32-ssDna Interactions. J. Biol. Chem. 281(36):26308-19.

7. Liu, J., Bond, J. P., and Morrical, S. W. (2006) Mechanism of presynaptic filament stabilization by the bacteriophage T4 UvsY recombination mediator protein. Biochemistry, 45(17), 5493-5502.

8. Bleuit, J.S., Xu, H., Ma, Y., Wang, T., Liu, J., & Morrical, S.W. (2001), Mediator proteins orchestrate enzyme-ssDNA assembly during T4 recombination-dependent DNA replication and repair.  Proc. Natl. Acad. Sci. U.S.A. 98, 8298-8305.