Publications › Kowalczykowski


BRCA2 is epistatic to the RAD51 paralogs in response to DNA damage.
Jensen RB, Ozes A, Kim T, Estep A, Kowalczykowski SC.
DNA Repair, 2013 Feb 2. doi:10.1016/j.dnarep.2012.12.007

Direct imaging of RecA nucleation and growth on single molecules of SSB-coated ssDNA.
Bell JC, Plank JL, Dombrowski CC, Kowalczykowski SC.
Nature, 2012 Nov 8; 491(7423):274-8. doi:10.1038/nature11598

RecFOR Proteins Target RecA Protein to a DNA Gap with Either DNA or RNA at the 5′ Terminus: Implication for Repair of Stalled Replication Forks.
Morimatsu K, Wu Y, Kowalczykowski SC.
Journal of Biological Chemistry, 2012 Oct 12; 287(42):35621-30. doi:10.1074/jbc.M112.397034
PMID:22902627 PMCID:PMC3471720

Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA Complex: A Mechanism for Disentangling Chromosomes.
Cejka P, Plank JL, Dombrowski CC, Kowalczykowski SC.
Molecular Cell, 2012 Sep 28; 47(6):886-96. doi:10.1016/j.molcel.2012.06.032
PMID:22885009 PMCID:PMC3462259

Saccharomyces cerevisiae Dmc1 and Rad51 Proteins Preferentially Function with Tid1 and Rad54 Proteins, Respectively, to Promote DNA Strand Invasion during Genetic Recombination.
Nimonkar AV, Dombrowski CC, Siino JS, Stasiak AZ, Stasiak A, Kowalczykowski SC.
Journal of Biological Chemistry, 2012 Aug 17; 287(34):28727-37. doi:10.1074/jbc.M112.373290
PMID:22761450 PMCID:PMC3436576

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress.
Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, Elledge SJ.
Molecular Cell, 2012 Aug 10; 47(3):396-409. doi:10.1016/j.molcel.2012.05.024

Molecular determinants responsible for recognition of the single-stranded DNA regulatory sequence, χ, by RecBCD enzyme.
Handa N, Yang L, Dillingham MS, Kobayashi I, Wigley DB, Kowalczykowski SC.
Proc Natl Acad Sci U S A, 2012 Jun 5; 109(23):8901-6. doi:10.1073/pnas.1206076109
PMID:22603794 PMCID:PMC3384139

Alteration of χ recognition by RecBCD reveals a regulated molecular latch and suggests a channel-bypass mechanism for biological control.
Yang L, Handa N, Liu B, Dillingham MS, Wigley DB, Kowalczykowski SC.
Proceedings of the National Academy of Sciences, 2012 Jun 5; 109(23):8907-12. doi:10.1073/pnas.1206081109

Translocation of E. coli RecQ Helicase on Single-Stranded DNA.
Rad B, Kowalczykowski SC.
Biochemistry, 2012 Apr 3; 51(13):2921-9. doi:10.1021/bi3000676
PMID:22409300 PMCID:PMC3330151

Single-molecule imaging of DNA pairing by RecA reveals a three-dimensional homology search.
Forget AL, Kowalczykowski SC.
Nature, 2012 Feb 8; 482(7385):423-7. doi:10.1038/nature10782
PMID:22318518 PMCID:PMC3288143

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