Publications › Xu


Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions.
Nera B, Huang HS, Lai T, Xu L.
Nat Commun. 2015 Dec 7;6:10132. doi: 10.1038/ncomms10132
PMID: 26640040

The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.
Frank AK, Tran DC, Qu RW, Stohr BA, Segal DJ, Xu L.
PLoS Genet. 2015 Jul 31;11(7):e1005410. doi: 10.1371/journal.pgen.1005410. eCollection 2015 Jul
PMID: 26230315; PMCID: PMC4521702

Highly active zinc-finger nucleases by extended modular assembly.
Bhakta MS, Henry IM, Ousterout DG, Das KT, Lockwood SH, Meckler JF, Wallen MC, Zykovich A, Yu Y, Leo H, Xu L, Gersbach CA, Segal DJ.
Genome Res. 2013 Mar;23(3):530-8. doi:10.1101/gr.143693.112.
PMCID: PMC3589541

The Role of Telomere Biology in Cancer.
Xu L, Li S, Stohr BA.
Annual Review of Pathology, 2013 Jan 24; 8:49-78. doi:10.1146/annurev-pathol-020712-164030

The Terminal Telomeric DNA Sequence Determines the Mechanism of Dysfunctional Telomere Fusion.
Stohr BA, Xu L, Blackburn EH.
Molecular Cell, 2010 Jul 30; 39(2):307-14. doi:10.1016/j.molcel.2010.06.020
PMID:20670897 PMCID:PMC2920734

Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy.
Wang X, Kam Z, Carlton PM, Xu L, Sedat JW, Blackburn EH.
Epigenetics & Chromatin, 2008 Oct 27; 1(1):4. doi:10.1186/1756-8935-1-4
PMID:19014413 PMCID:PMC2585561

Human Cancer Cells Harbor T-Stumps, a Distinct Class of Extremely Short Telomeres.
Xu L, Blackburn EH.
Molecular Cell, 2007 Oct 26; 28(2):315-27. doi:10.1016/j.molcel.2007.10.005
PMID:17964269 PMCID:PMC2081152

Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules.
Xu L, Blackburn EH.
Journal of Cell Biology, 2004 Dec 6; 167(5):819-30. doi:10.1083/jcb.200408181
PMID:15583028 PMCID:PMC2172464

Catalytically active human telomerase mutants with allele-specific biological properties.
Kim M, Xu L, Blackburn EH.
Experimental Cell Research, 2003 Aug 15; 288(2):277-87. doi:10.1016/S0014-4827(03)00217-9

A role for a novel ‘trans-pseudoknot’ RNA–RNA interaction in the functional dimerization of human telomerase.
Ly H, Xu L, Rivera MA, Parslow TG, Blackburn EH.
Genes & Development, 2003 May 1; 17(9):1078-83. doi:10.1101/gad.1060803
PMID:12730131 PMCID:PMC196051

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