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Privalsky

Corepressor diversification by alternative mRNA splicing is species specific.
Privalsky ML, Snyder CA, Goodson ML.
BMC Evol Biol. 2016 Oct 19;16(1):221
PMID: 27756201; PMCID: PMC5069798


Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling.
Snyder CA, Goodson ML, Schroeder AC, Privalsky ML.
Mol Cell Endocrinol. 2015 Sep 15;413:228-35. doi: 10.1016/j.mce.2015.06.036. Epub 2015 Jul 10
PMID: 26166430


Alteration of NCoR corepressor splicing in mice causes increased body weight and hepatosteatosis without glucose intolerance.
Goodson ML, Young BM, Snyder CA, Schroeder AC, Privalsky ML.
Mol Cell Biol. 2014 Sep 2. doi: 10.1128/MCB.00554-14. [Epub ahead of print]
PMID: 25182530


Thyroid Hormones, T3 and T4, in the Brain.
Schroeder AC, Privalsky ML.
Front Endocrinol (Lausanne). 2014 Mar 31;5:40. eCollection 2014. Review
PMID: 24744751; PMCID: PMC3978256


The ability of thyroid hormone receptors (TRs) to sense T4 (3,5,3′,5′-tetraiodo-thyronine) as an agonist depends on receptor isoform and on cellular cofactors.
Schroeder A, Jimenez R, Young B, Privalsky ML.
Mol Endocrinol. 2014 Mar 27. [Epub ahead of print]
PMID: 24673558


The two major isoforms of thyroid hormone receptor, TRα1 and TRβ1, preferentially partner with distinct panels of auxiliary proteins.
Hahm JB, Schroeder AC, Privalsky ML.
Mol Cell Endocrinol. 2013 Dec 8;383(1-2):80-95. doi10.1016/j.mce.2013.11.015
PMID:24325866


Research Resource: Identification of novel coregulators specific for thyroid hormone receptor-β2.
Hahm JB, Privalsky ML.
Mol Endocrinol. 2013 Apr 4. [Epub ahead of print]
PMID: 23558175


Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.
Sinha RA, You SH, Zhou J, Siddique MM, Bay BH, Zhu X, Privalsky ML, Cheng SY, Stevens RD, Summers SA, Newgard CB, Lazar MA, Yen PM.
Journal of Clinical Investigation, 2012 Jul 2; 122(7):2428-38. doi:10.1172/JCI60580
PMID:22684107 PMCID:PMC3386813


SMRTε, a corepressor variant, interacts with a restricted subset of nuclear receptors, including the retinoic acid receptors α and β.
Mengeling BJ, Goodson ML, Bourguet W, Privalsky ML.
Molecular and Cellular Endocrinology, 2012 Apr 4; 351(2):306-16. doi:10.1016/j.mce.2012.01.006
PMID:22266197 PMCID:PMC3288673


Alternative mRNA Splicing of Corepressors Generates Variants That Play Opposing Roles in Adipocyte Differentiation.
Goodson ML, Mengeling BJ, Jonas BA, Privalsky ML.
Journal of Biological Chemistry, 2011 Dec 30; 286(52):44988-99. doi:10.1074/jbc.M111.291625
PMID:22065574 PMCID:PMC3247966


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