Undergraduate and Graduate Courses in Microbiology

Lower Division Courses . . Upper Division Courses . . Graduate Courses . . Professional Course


Lower Division Courses

10. Natural History of Infectious Diseases (3)
Lecture—3 hours. Topics in the natural history of infectious diseases principally affecting humans. Introduction to infectious microbial agents, ecology, epidemiology, and induction of disease. Focus on diseases of a contemporary nature. For students not majoring in the biological sciences. Not open for credit to students who have completed course 101 or course 102. GE credit: SciEng.—III. (III.) Mann

91. Introduction to Research (1)
Seminar—1 hour. Prerequisite: Biological Sciences 1A or 2A or consent of instructor. Discussion of faculty research focusing on the biochemistry, genetics, and cell biology of microorganisms, along with ways undergraduates can participate in research projects of faculty members. May be repeated three times for credit.
(P/NP grading only.)—III. (III.) Lin, Xu

98. Directed Group Study (1-5)
Prerequisite: consent of instructor. Primarily for lower division students. (P/NP grading only.)

99. Special Study for Undergraduates (1-5)
(P/NP grading only.)


Upper Division Courses

101. Introductory Microbiology (5)
Lecture—4 hours; laboratory—3 hours. Prerequisite: Biological Sciences 1A, or 2A and Chemistry 2B (Chemistry 2B may be taken concurrently). Survey of microorganisms emphasizing their interactions with humans and diseases. Topics include microscopy, survey of various microbes, the immune system, food microbiology, microbial pathogens, and mechanisms of disease transmission. Designed for students requiring microbiology for professional schools. Not open for credit to students who have completed course 102 or 102L.—II, II, III. (I, II, III.) Mann, Navarro

104. General Microbiology (4)
Lecture—4 hours. Prerequisite: Biological Sciences 101; 103 or 105. Designed for students continuing in microbiology
or using microorganisms as tools for the study of genetics and biochemistry. Biology of microorganisms, including viruses, archaea, bacteria, and eukaryotic microbes. Topics include microbial structure, growth, antibiotics, pathogenesis, immunology, and epidemiology. Only two units of credit for students who have taken course 101. Not open for credit to students who have completed course 102.—I. (I.) Stewart

104L. General Microbiology Laboratory (3)
Lecture-1 hour; laboratory-6 hours. Prerequisite: course 102 or 104 (may be taken concurrently); consent of instructor. Students must complete a petition for consideration of enrollment; petition available on Department of Microbiology website. Introduction to principles and laboratory methods in microbiology. Designed for students continuing in microbiology or using microorganisms as tools for the study of genetics and biochemistry. In combination with course 104, fulfills the microbiology requirement for professional schools. Only two units of credit allowed to students who have completed course 101. Not open to students who have completed course 102L.—I. (I) Igo, Nelson

105. Microbial Diversity (3)
Lecture—3 hours. Prerequisite: course 102 or 104;  Biological Sciences 103 or 105. Survey of microbial diversity in the three domains of Life: Bacteria, Archaea, and microbial eukaryotes. Emphasizes microbial evolution and phylogeny, physiology and metabolism, global biogeochemical cycles, environmental adaptations, and genomic methods for analyzing culture-independent microbial diversity and microbial communities. —II. (II.) Dawson, Parales

105L. Microbial Diversity Laboratory (3)
Lecture-1hour; Laboratory—6 hours. Prerequisite: course 102 or 104; 102L or 104L; 105 (may be taken concurrently); Biological Sciences 103 or 105. Students must complete a petition in order for consideration of enrollment; petition   available on the Department of Microbiology website. Classical enrichments for the isolation of metabolically diverse microbes; modern molecular methods for the identification of isolates; cultivation independent analysis of microbial communities from local environmental samples.—II. (II.) Dawson, Parales

115. Recombinant DNA Cloning and Analysis (3)
Lecture—3 hours. Prerequisite: Biological Sciences 101 or equivalent. Cloning and analysis of recombinant DNA, with emphasis on Escherichia coli host-vector systems. DNA-modifying enzymes; vectors and their use; manipulation and expression of insert DNA; polymerase chain reaction; and sequence annotation. Graduate students see course 215. Not offered every year. I. (I.) Xu

120. Microbial Ecology (3)
Lecture—3 hours. Prerequisite: course 105, Biological Sciences 102 or 105. Interactions between non-pathogenic microorganisms and their environment, emphasizing physiological and metabolic characteristics of various groups and their adaptation to and modification of specific habitats. Not offered every year. —III. (III.) Nelson

150. Bacterial Genetics (3)
Lecture—3 hours. Prerequisite: Biological Sciences 101,102, Biological Sciences 103 or Microbiology 140; Microbiology 102 recommended. Molecular genetics of enterobacteria and their viruses. Isolation of mutants; genetic exchange and mapping; complementation; suppression; transposons; gene expression and regulation; and genomics. Examples will illustrate applications to molecular cloning of recombinant DNA, and to the study of bacterial pathogenesis. Not offered every year.

162. General Virology (4)
Lecture—4 hours. Prerequisite: Biological Sciences 102 or 105. Integrated presentation of the nature of animal, bacterial, and plant viruses, including their structure, replication and genetics. Only three units to students who have completed Pathology, Microbiology, and Immunology 128.—II. (II.) Falk, Manning

170. Yeast Molecular Genetics (3)
Lecture—3 hours. Prerequisite: Biological Sciences 101; 102 or 105; Microbiology 102 or 140 strongly recommended. Survey of the genetics, cell biology and technologies in yeasts and related lower eukaryotes. Topics include diversity of yeasts; cell structure; metabolism; cell cycle; genetic approaches and genomics; gene expression; yeasts as models to study higher eukaryotes; and contemporary techniques.—III. (III.) Lin

190C. Undergraduate Research Conference (1)
Discussion—1 hour. Prerequisite: upper division standing and consent of instructor, course 199 concurrently. Presentation and critical discussion of staff research activities: designed for advanced undergraduate students. May be repeated for credit. (P/NP grading only.)—I, II, III. (I, II, III.)

191. Introduction to Research for Advanced Undergraduates (1)
Seminar—1 hour. Prerequisite: Biological Sciences 1A or 2A or consent of instructor. Discussion of faculty research focusing on the biochemistry, genetics, and cell biology of microorganisms, along with ways undergraduates can participate in research projects of faculty members. May be repeated three times for credit. (P/NP grading only.)—III. (III.) Lin, Xu

192. Internship (1-12)
Internship—3-36 hours. Technical and/or professional experience on or off campus. Supervised by a member of the Microbiology Department faculty. (P/NP grading only.)

194H. Microbiology Honors Research (2)
Independent study—6 hours. Prerequisite: senior standing; eligibility for college honors; completion of six units of 199 in microbiology; consent of Department. Continuation of an individual microbiological research project culminating in writing of a senior thesis under a faculty director. (P/NP grading only.)—I, II, III. (I, II, III.)

197T. Tutoring in Microbiology (1-12)
Prerequisite: upper division standing and consent of instructor. Assisting the instructor in one of the Department’s regular courses by tutoring individual or small groups of students in a laboratory, in voluntary discussion groups, or other voluntary course activities. May be repeated for credit. (P/NP grading only.)—I, II, III. (I, II, III.)

198. Directed Group Study (1-5)
Prerequisite: consent of instructor. (P/NP grading only.)

199. Special Study for Advanced Undergraduates (1-5)
Prerequisite: consent of instructor. (P/NP grading only.)—I, II, III. (I, II, III.)


Graduate Courses

200A. Biology of Prokaryotes (3)
Lecture—3 hours. Prerequisite: course 102 or the equivalent. Intended for first year graduate students in microbiology and closely related fields. Overview of prokaryotic biology, with emphasis on phylogeny, physiology, and diversity of bacteria. Not offered every year —I. (I.)

200B. Advanced Bacteriology (3)
Lecture—3 hours. Prerequisite: course 200A. Intended for first year graduate students in microbiology and closely related fields. Advanced topics in phylogeny, physiology, and diversity of bacteria. Not offered every year.—II. (II.)

201L. Advanced Microbiology Laboratory Rotations (5)
Laboratory—15 hours. Prerequisite: course 200A (may be taken concurrently). Two five-week assignments in microbiology research laboratories. Individual research problems with emphasis on methodological/procedural experience and experimental design. May be repeated two times for credit.—I, II. (I, II.)

210. Molecular Mechanisms in Microbial Pathogenesis (3)
Lecture—3 hours. Prerequisite: course 105 or Veterinary Microbiology 127 and course 162 or Veterinary Microbiology 128 or the equivalent. Study of the molecular mechanisms involved in cytopathogenesis of higher eukaryotic organisms. Emphasis on the alteration or inhibition of cellular metabolism and function by bacteria and animal viruses. Not offered every year.

215. Recombinant DNA (3)
Lecture—3 hours. Prerequisite: Biological Sciences 101, 102, 103 or the equivalent. Application of recombinant DNA technology to modern problems in biology, biochemistry, and genetics, emphasizing molecular cloning strategies, choice of vectors, preparation of insert DNA, and selection procedures.—I. (I.) Privalsky

250. Biology of Yeasts (5)
Lecture—3 hours; discussion—2 hours. Prerequisite: Biological Sciences 102, 103; course 102, 102L; course 215 recommended. Survey of the genetics, physiology, metabolism, regulatory mechanisms, structure, cell biology, ecology and diversity of yeasts and related organisms. Not offered every year.

260. Bacterial Genetic Regulatory Mechanisms (3)
Lecture/discussion—3 hours. Prerequisite: general knowledge of nucleic acid biochemistry and bacterial genetics. Analysis at the molecular level of genetic regulation in selected bacterial systems. Specific systems discussed will include the following types of regulation: control of transcription initiation and termination; translational controls; tRNA modification effects; autoregulation; control circuits in bacterial viruses; supercontrols. Not offered every year.

262. Advanced General and Molecular Virology (3)
Lecture—3 hours. Prerequisite: graduate standing. Advanced integrated presentation of animal, bacterial, and plant viruses, including their structure, modes of regulation, expression and replication, and effects on host cells and organisms.—II. Offered in alternate years. Luciw

263. Principles of Protein–Nucleic Acid Interactions (3)
Lecture—3 hours. Prerequisite: advanced graduate standing and completion of one year of basic graduate course work in biochemistry, biophysics, chemistry, genetics, microbiology, or molecular biology. Physical basis of protein–nucleic acid interaction. Topics include nucleic acid recognition by proteins, thermodynamics of protein–nucleic acid stability, and kinetics of binding process for both non-specific and sequence-specific nucleic acid binding proteins. Emphasis on systems that represent paradigms in protein–nucleic acid interactions. Not offered every year. Kowalczykowski

274. Seminar in Genetic Recombination (1)
Seminar—1 hour. Prerequisite: graduate standing; consent of instructor. Biochemical and genetic aspects of genetic recombination in prokaryotes and eukaryotes. Mechanisms of recombination and biochemical and genetic characteristics of recombination proteins. Proteins include DNA strand exchange, DNA helicases, and Holliday junction resolving proteins. May be repeated for credit. Not offered every year. (S/U grading only.) Kowalczykowski

275. Seminar in DNA Repair and Recombination (1)
Seminar—1 hour. Prerequisite: consent of instructor; graduate standing in Microbiology or closely related field. Review and discussion of current research and literature in DNA repair and recombination with presentations by individual students and invited speakers. May be repeated for credit. (S/U grading only.)—(I, II, III.) Heyer

276. Advanced Concepts in DNA Metabolism (3)
Lecture—3 hours. Prerequisite: Molecular and Cellular Biology 221C or Genetics 201C or equivalent course recommended. DNA damage checkpoints, homologous recombination, and meiotic recombination. An advanced treatment of the clinical and current literature to discuss emerging principles and current models in these research areas. Offered in alternate years.—III. Heyer

290C. Advanced Research Conference (1)
Discussion/conference—1 hour. Prerequisite: graduate standing and/or consent of instructor. Presentation and critical discussion of staff research activities. Designed for advanced graduate students. May be repeated for credit. (S/U grading only.)—I, II, III. (I, II, III.)

291. Selected Topics in Microbiology (1)
Seminar—1 hour. Prerequisite: graduate standing and consent of instructor. Current progress in microbiology and cellular and molecular biology. May be repeated for credit. (S/U grading only.)—I, II, III. (I, II, III.)

292. Seminar in Bacterial Physiology and Genetics (1)
Seminar—1 hour. Prerequisite: consent of instructor, graduate standing in microbiology or closely related field. Review and discussion of current research and literature in bacterial physiology and genetics, with presentations by individual students. (S/U grading only.)—I, II, III. (I, II, III.)

298. Group Study (1-5)
Prerequisite: consent of instructor. (S/U grading only.)—I, II, III. (I, II, III.)

299. Research (1-12)—I, II, III. (I, II, III.)
(S/U grading only.)


Professional Course

396. Teaching Assistant Training Practicum (1-4)
Prerequisite: graduate standing. May be repeated for credit. (S/U grading only.)—I, II, III. (I, II, III.)